Author: QuadShot News
A new fellowship track is coming, with a systematic analysis of a global database of skin cancers from 1990 to 2021 demonstrating a steady increase in incidence of melanoma and non-melanoma skin cancers, largely in accordance with aging population increases, with non-melanoma skin cancers projected to cause more deaths than melanoma by 2050. | Wang, JAMA Dermatol 2025
Does anyone else read this week’s widely-circulated article on prostate cancer screening and feel like you’re time traveling to the 1990s? Are we now ignoring the years of work developing and finessing tools to such as multiparametric prostate MRIs and individualized detailed PSA analyses to successfully slash the rate of clinically meaningless prostate biopsies, all in order to stick with political talking points de jour that—randomly, today—suit one side versus another? Thankfully, radiologist Dr. Koo is quoted stating the undeniable: “the risk-benefit analysis for screening has changed in recent years,” while recognizing another crucial piece of the puzzle, namely that…
Top Line: What is the rate of post-op wound complication following hypofractionated radiation for soft tissue sarcoma?The Study: Neoadjuvant radiation is often employed prior to resection of extremity and superficial soft tissue sarcoma to reduce recurrence risk. Compared to adjuvant RT, neoadjuvant RT is often shorter and has less long-term toxicity, but it has a higher risk of wound complications. MC1973 was a phase 2 trial of 120 patients with resectable extremity (48.7% proximal lower extremity) or superficial trunk STS who were planned to receive neoadjuvant RT. The RT regimen was 42.75 Gy in 15 fractions over 3 weeks. The…
The news was shared by his personal office late Sunday including the fact it is Gleason 9 and metastatic to the bone, leaving everyone wishing him the best…while wondering how extremely low burden PSA surveillance was omitted for the leader the free world who was vying to keep that position until 2029. | Klein, CNN 2025
A randomized trial reported non-inferior local control with simple hysterectomy (sparing parametria and upper vagina and thus urinary toxicity) versus the historic standard of radical hysterectomy for early-stage IA2-IB1 cervical cancer, but there weren’t enough events to power a survival analysis. This NCDB analysis supports similar long term survival for stage IA2-IB1 cervical cancer with stromal invasion <1 cm regardless of surgical extent. | Tarney, JAMA Netw Open 2025
Top Line: Lung SBRT is pretty standard at this point, right?The Study: Well, there is actually quite a bit of variation across centers and around the world when it comes to lung SBRT. This huge international patterns of care survey, which consisted of 35 questions about patients selection, treatment planning, and clinical scenarios, was completed by 255 radiation oncologists representing 255 different centers across 51 countries. The median number of lung SBRT cases per year was 20. Two-thirds (67.5%) had a specific size cutoff for lung SBRT with a mean cutoff of 5.5 cm. Only 21% used IV contrast during…
The news was shared by his personal office late Sunday including the fact it is Gleason 9 and metastatic to the bone, leaving everyone wishing him the best…while wondering how extremely low burden PSA surveillance was omitted for the leader the free world who was vying to keep that position until 2029. | Klein, CNN 2025
A randomized trial reported non-inferior local control with simple hysterectomy (sparing parametria and upper vagina and thus urinary toxicity) versus the historic standard of radical hysterectomy for early-stage IA2-IB1 cervical cancer, but there weren’t enough events to power a survival analysis. This NCDB analysis supports similar long term survival for stage IA2-IB1 cervical cancer with stromal invasion <1 cm regardless of surgical extent. | Tarney, JAMA Netw Open 2025
Top Line: Lung SBRT is pretty standard at this point, right?The Study: Well, there is actually quite a bit of variation across centers and around the world when it comes to lung SBRT. This huge international patterns of care survey, which consisted of 35 questions about patients selection, treatment planning, and clinical scenarios, was completed by 255 radiation oncologists representing 255 different centers across 51 countries. The median number of lung SBRT cases per year was 20. Two-thirds (67.5%) had a specific size cutoff for lung SBRT with a mean cutoff of 5.5 cm. Only 21% used IV contrast during…
The news was shared by his personal office late Sunday including the fact it is Gleason 9 and metastatic to the bone, leaving everyone wishing him the best…while wondering how extremely low burden PSA surveillance was omitted for the leader the free world who was vying to keep that position until 2029. | Klein, CNN 2025