This institution implemented bone dose constraints years back after observing a 4.5% rate of fracture in patients with soft tissue sarcoma. A look back at 700 patients treated since implementation found a fracture rate of just 1.4% at a median 4.5 years after treatment. Notably, half of those fractures occurred in patients who either exceeded constraints or underwent re-irradiation. | Othman, Int J Radiat Oncol Biol Phys 2025

