Browsing: Central Nervous System

This retrospective look at 94 consecutive patients with melanoma brain mets resected at UCSF aimed to characterize which intracranial features…

Myeloid derived immune suppressor cells (MDSCs) in the tumor microenvironment of glioblastoma multiforme (GBM) dampen the efficacy of oncologic therapies.…

Top Line: What is the intracranial activity of chemoimmunotherapy for untreated NSCLC brain metastases? The Study: Systemic therapy won’t be…

Top Line:Tucatinib is increasingly used as part of combination systemic therapy for metastatic HER2+ breast cancer with impressive intracranial activity.…

Top Line: Fractionated SRS is often used to reduce the risk of radiation necrosis (RN), but that risk isn’t zero.…

Hippocampal avoidance reduces neurocognitive toxicity from whole brain radiation, but many patients still experience cognitive decline. This small phase 2…

Top Line:Vestibular schwannomas are the most common tumors of the cerebellopontine angle, and most are small to medium with options…

While we’re all very comfortable with SRS for NSCLC, there is still controversy whether SRS should be used first-line for…

Numerous trials have failed to improve treatment outcomes by escalating dose beyond 60 Gy for GBM. In the SPECTRO GLIO…

Here is a patient perspective on why more efforts should be devoted to the advancement of care of patients with…