Browsing: Central Nervous System

This editorial is here to remind us level I randomized evidence from NRG-RTOG 1114 supports reintroducing low-dose whole brain radiation…

When patients with ES-SCLC develop brain only progression, should they switch systemic therapy along with brain radiation? This multicenter cohort…

A large pooled analysis confirms longer non-steroidal anti-androgen (e.g. bicalutamide) use in conjunction with LHRH agonists (e.g. Lupron) beyond the…

Top Line: Does dose escalation with intraoperative radiation in additional to standard chemoradiation improve outcomes in patients with GBM?The Study:…

A prospectively-collected database of 371 patients with extensive-stage small cell lung cancer without baseline brain metastases reports chemoimmunotherapy improved overall…

This single institution series of 299 resected brain metastases in 260 patients treated with preoperative SRS found similar rates of…

A large retrospective cohort of patients receiving brain radiosurgery suggests lesions that enlarge later (median 8 versus 6 months), occur…

Risk-adapted meningioma management leans on grade, extent of resection, and recurrence status. RTOG 0539 prospectively stratified 165 patients into three…

Top Line: Single-isocenter multi-target radiosurgery has become increasingly attractive as we treat patients with ever-growing numbers of brain metastases, but…

A Tata Memorial phase 3 randomized trial of 208 patients with oncogene (read: ALK or EGFR)-driven non-small cell lung cancer…