Browsing: Gastrointestinal

The SKYSCRAPER trials have been investigating dual immune checkpoint inhibition with atezolizumab and the TIGIT inhibitor tiragolumab. We recently saw…

Top Line: Radiotherapy has had a tough time establishing its incremental value when added to modern neoadjuvant chemotherapy for resectable…

A population-based study reports cancer mortality declined among Canadians aged 20–49 years for 9 of the 10 leading cancer primaries…

Top Line: More data support moving chemotherapy prior to surgery for locally-advanced rectal cancer.The Study: RAPIDO established a total neoadjuvant…

Top Line: For small, node-negative rectal cancers, can we spare the rectum entirely, and does it matter whether we get…

Top Line: When and how to dose-esclate radiation for pancreatic cancer is becoming increasingly complex.The Study: Enter the latest ASTRO…

In this retrospective cohort of 13,258 patients with pancreatic cystic neoplasms, surveillance practices de-escalated substantially over time, with declining endoscopic…

Histotripsy is a nonthermal, noninvasive, focused ultrasound that supposedly mechanically disrupts tumors. What could go wrong? This retrospective study evaluated…

In the RAPIDO trial of short course RT and TNT for rectal cancer, radiation planning was physician preference with no…

A single-arm phase 2 trial at MSKCC suggests hypofractionated ablative radiation (4.5 Gy x 15 = 67.5 Gy if >1…