An analysis of U.S. mortality data from 1990–2023 reveals, while overall cancer death rates in people younger than 50 have precipitously declined by 44%–largely explained by miraculous treatment advancements in breast and lung cancers–colorectal cancer sticks out like a sore thumb as the only disease with mortality steadily rising since 2005, now surpassing even breast cancer as the leading cause of cancer death in this age group. | Siegel, JAMA 2026
