Patients with symptomatic aggressive B cell lymphoma planned for CAR-T cell therapy can benefit from the rapid relief afforded with bridging radiation. A well-meaning medical oncologist may have concerns that resulting radiation lymphopenia could adversely impact outcomes with subsequent systemic therapy. This detailed look back at 51 patients receiving bridging radiation prior to CAR-T could find no correlation between lymphocyte count drop after radiation and 30 or 90 day response or any disease or survival outcomes. | Manzar, Int J Radiat Oncol Biol Phys 2024
