Machine learning of digital histopathology of colon adenocarcinoma has identified a novel and quantifiable “tumor adipose feature” (moderately to poorly differentiated tumor cells in close proximity to adipocytes) that is prognostic of survival, and this retrospective look at 258 cases treated in Milan demonstrates this feature is reliably measured by pathologists and retains its prognostic value. | L’Imperio, JAMA Netw Open 2023