A large multi-institutional retrospective cohort reports patients receiving radiosurgery for brain mets from gastrointestinal primaries have half the rate of intracranial progression-free survival (median of 6 months) as non-GI primary sites (12 months) despite only 2% (n=2) experiencing local failure, suggesting these patients are at high risk for distant brain failure and may warrant enhanced post-treatment imaging surveillance. | Qazi, Adv Radiat Oncol 2025
