An eyebrow-raising secondary analysis of five pooled clinical trials for glioblastoma multiforme demonstrates robust detriments in overall survival for patients on PPIs–such as those obscure drugs omeprazole and pantoprazole–known to potently-induce protection from oxidative stress (i.e., the mechanism of action of radiotherapy and many chemotherapies). | Le Rhun, JAMA Netw Open 2025
