In this phase 1 feasibility trial, 16 patients requiring urgent radiation for epidural spinal cord compression received initial conformal RT with 20 Gy in 5 fractions or 8 Gy in 1 fraction. Within 6 weeks, they received an SBRT boost of 18-24 Gy in 2 fractions. The majority of patients either maintained (76.9%) or had improved motor function (15.4%) following the completion of treatment. Only one patient had a grade 3 adverse event (chest pain). | Donovan, Int J Radiat Oncol Biol Phys 2025
