This retrospective analysis of 382 such cases at UPMC concludes prior diagnostic tonsillectomy before trans-oral robotic surgery for HPV+ tonsillar squamous cell carcinoma did not increase risk of final involved margin or worsen survival compared to upfront TORS, supporting tonsillectomy as a safe diagnostic step that does not compromise oncologic outcomes. | Harris, JAMA Otolaryngol Head Neck Surg 2026
