Does it matter whether Pd-103 or I-125 are used for prostate brachytherapy? The two are commonly used in the US for prostate brachytherapy. Pd-103 has a slightly lower energy and much lower half life than I-125 (17 v 60 days). Using a retrospective database of >9000 men treated with prostate brachytherapy from 8 institutions, this study compared clinical outcomes with each isotope. Patients treated with Pd-103 had a significantly higher rate of freedom from biochemical failure (96.2% v 87.6%) and freedom from clinical failure (96.5% v 94.3%) at 7 years. | Tang, Radiother Oncol 2023
