If anything could identify whether tumor motion influences recurrence risk, it’s single fraction lung SBRT where you have one shot to hit a moving target. An analysis of the iSABR trial found no difference in recurrence for tumors that moved <1cm or >1cm (5.8% v 6.3%). There were also no differences between motion inclusive (5.5%), motion inclusive with extremes excluded (5.9%), expiratory gating (4.7%), or inspiratory breath hold (3.7%). | Jaoude, Int J Radiat Oncol Biol Phys 2025
