Infertility is one of the most consequential long term toxicities of several oncologic therapies used in premenopausal women and girls. Here is an excellent summary on the contemporary options available across a myriad of scenarios from taking a break during maintenance endocrine therapy to preemptive cryopreservation of oocytes/embryos or ovarian tissue (when prepubertal) prior to initiation of follicle-damaging chemotherapy or radiation. Future directions are also touched on, including in vitro follicle maturation, ovarian grafting, ovarian-protecting agents, and newly-discovered ovarian stem cells. | Rodriguez-Wallberg, Life 2023
