NCCN guidelines are pretty vague on the best strategy to follow our head and neck patients to catch early recurrence while minimizing follow-up burden. One reason is that this patient population is quite the mixed bag. A retrospective look at 340 patients achieving a complete PET response to definitive head and neck radiation demonstrated no difference in disease-free or overall survival at 3 years when comparing patients undergoing routine interval surveillance imaging (n=187) versus those undergoing clinical follow-up only (n=153). | Chen, JAMA Netw Open 2023
