Browsing: TNT

Top Line: More data support moving chemotherapy prior to surgery for locally-advanced rectal cancer.The Study: RAPIDO established a total neoadjuvant…

In the RAPIDO trial of short course RT and TNT for rectal cancer, radiation planning was physician preference with no…

Top Line: Total neoadjuvant therapy is now well established as the preferred treatment for patients with high risk, locally advanced…

Here is another sweeping review to walk us through the evolution from upfront total mesorectal excision ± radiation to modern…

Top Line: The management of locally advanced rectal cancer has become extremely nuanced over the past few years.The Study: Here…

In the OPRA trial, 74% of rectal cancer patients had a complete or near-complete response to total neoadjuvant therapy and…

Headline: Immunotherapy may improve response rates to total neoadjuvant therapy for rectal cancer.The Study: Multiple recent trials have shown encouraging…

Top Line: Are there differences in survival outcomes when non-operative management is offered rather than mandatory surgery following total neoadjuvant…

A secondary analysis of a phase 3 trial comparing standard long-course chemoradiation alone (CRT) versus short-course radiation followed by CAPOX…

Top Line: Is short-course or long-course radiation better for organ preservation when delivering total neoadjuvant therapy for rectal cancer?The Study:…