What was the rate of acute grade 3+ GI toxicity in a recent trial of hypofractionated pelvic radiation for cervical cancer?
In a large meta-analysis of ADT duration, the absolute benefit of prolonged ADT seems to fall off around what time period?
Does vorasidenib improve seizure control in patients with IDH-mutated, grade 2 glioma?
In the NO-CUT trial, what was the rate of distant relapse free survival at 30 months with nonoperative management of locally advanced rectal cancer?
Answers
20% with 40 Gy in 16 fractions with a 10 Gy in 4 fractions boost to gross nodes and 28 Gy in 4 fractions brachytherapy boost.
12 months. Beyond this, the absolute benefit in PCSM decreased relative to increases in other cause mortality.
Yes, seizure episodes per person year were more than halved. However, there were no improvements (or detriment) in quality of life outcomes.
95%. They were treated with CapeOx and long course CRT, but importantly they had strict response criteria such that only 26% had a complete response and went on to nonoperative management. | QuadShot News
In a large meta-analysis of ADT duration, the absolute benefit of prolonged ADT seems to fall off around what time period?
Does vorasidenib improve seizure control in patients with IDH-mutated, grade 2 glioma?
In the NO-CUT trial, what was the rate of distant relapse free survival at 30 months with nonoperative management of locally advanced rectal cancer?
Answers
20% with 40 Gy in 16 fractions with a 10 Gy in 4 fractions boost to gross nodes and 28 Gy in 4 fractions brachytherapy boost.
12 months. Beyond this, the absolute benefit in PCSM decreased relative to increases in other cause mortality.
Yes, seizure episodes per person year were more than halved. However, there were no improvements (or detriment) in quality of life outcomes.
95%. They were treated with CapeOx and long course CRT, but importantly they had strict response criteria such that only 26% had a complete response and went on to nonoperative management. | QuadShot News