A recent analysis of the arms from RTOG 9804 and E5194 found that endocrine therapy reduced the risk of ipsilateral breast tumor recurrence by how much when compared to surgery alone without RT?
What was the risk of local recurrence after whole breast RT with concurrent boost in RTOG 1005?
What was the rate of grade 2 or higher nausea with prophylactic olanzapine versus without in patients receiving abdominal or pelvic radiation?
Answers
11.4% v 19% at 15 years. This is comparable to the reduction in recurrence risk with radiation alone in older trials that included higher risk patients.
2.6% v 2.2% at 7 years with 40.05 Gy in 15 fractions and a concurrent boost of 48 Gy in 15 fractions.
7.4% v 67% without. Olanzapine 5mg daily along with 4mg ondansetron significant reduced nausea and emesis with higher mild drowsiness, dysarthria, and hypotension. | QuadShot News
What was the risk of local recurrence after whole breast RT with concurrent boost in RTOG 1005?
What was the rate of grade 2 or higher nausea with prophylactic olanzapine versus without in patients receiving abdominal or pelvic radiation?
Answers
11.4% v 19% at 15 years. This is comparable to the reduction in recurrence risk with radiation alone in older trials that included higher risk patients.
2.6% v 2.2% at 7 years with 40.05 Gy in 15 fractions and a concurrent boost of 48 Gy in 15 fractions.
7.4% v 67% without. Olanzapine 5mg daily along with 4mg ondansetron significant reduced nausea and emesis with higher mild drowsiness, dysarthria, and hypotension. | QuadShot News