Is RT alone or temozolomide alone superior in the treatment of different molecular subtypes of low grade glioma?
What was the rate of PFS at 2 years in the DART trial of radiation and durvalumab for NSCLC patients who weren’t candidates for chemoradiation?
Does a modest SIB improve response or control for locally advanced rectal cancer?
In the RAPCHEM trial, what nodal volumes were treated in breast cancer patients who had pN1 disease after neoadjuvant therapy?
Answers
No. Long term follow up of EORTC 22033 with post hoc molecular classification showed similar survival between both solo modalities for IDH-mutated, codeleted and IDH-mutated, noncodeleted tumors.
39%. While not impressive at first glance, it beat out historical control and recall that the population was much older and had worse performance status than those who are CRT candidates.
Possibly. In this phase 2 trial, an SIB of 56 Gy in 28 fractions to the primary and up to 60 Gy to lateral pelvic nodes had similar pCR rate but significantly higher locoregional control and DFS.
Axilla levels I and II. Long term outcomes of RAPCHEM showed excellent control with a response adapted approach to adjuvant radiation. | QuadShot News
What was the rate of PFS at 2 years in the DART trial of radiation and durvalumab for NSCLC patients who weren’t candidates for chemoradiation?
Does a modest SIB improve response or control for locally advanced rectal cancer?
In the RAPCHEM trial, what nodal volumes were treated in breast cancer patients who had pN1 disease after neoadjuvant therapy?
Answers
No. Long term follow up of EORTC 22033 with post hoc molecular classification showed similar survival between both solo modalities for IDH-mutated, codeleted and IDH-mutated, noncodeleted tumors.
39%. While not impressive at first glance, it beat out historical control and recall that the population was much older and had worse performance status than those who are CRT candidates.
Possibly. In this phase 2 trial, an SIB of 56 Gy in 28 fractions to the primary and up to 60 Gy to lateral pelvic nodes had similar pCR rate but significantly higher locoregional control and DFS.
Axilla levels I and II. Long term outcomes of RAPCHEM showed excellent control with a response adapted approach to adjuvant radiation. | QuadShot News