In the NEOTRAC study, did neoadjuvant RT following neoadjuvant systemic therapy for HER2 positive breast cancer improve response rates?
What was the rate of acute grade 2+ GU effects following SBRT with an empty bladder for prostate cancer in the EMPTY-RT study?
What is the optimal LAD Dmax to minimize the risk of adverse cardiac events from left breast radiation?
Answers
No. Granted surgery was 4-6 weeks after RT, but there was no increase in pathologic complete response.
28%, which came in under the historical control of 32%.
12 Gy EQD2, or about 10.5 Gy in 15 fractions or 7 Gy in 5 fractions. Baseline cardiac risk factors were the overwhelming driver of cardiac events, but among dosimetric factors LAD Dmax was more strongly associated with cardiac risk than mean heart dose. | QuadShot News
What was the rate of acute grade 2+ GU effects following SBRT with an empty bladder for prostate cancer in the EMPTY-RT study?
What is the optimal LAD Dmax to minimize the risk of adverse cardiac events from left breast radiation?
Answers
No. Granted surgery was 4-6 weeks after RT, but there was no increase in pathologic complete response.
28%, which came in under the historical control of 32%.
12 Gy EQD2, or about 10.5 Gy in 15 fractions or 7 Gy in 5 fractions. Baseline cardiac risk factors were the overwhelming driver of cardiac events, but among dosimetric factors LAD Dmax was more strongly associated with cardiac risk than mean heart dose. | QuadShot News