In a recent trial of proton therapy for patients with resected HNSCC, was mucositis lower than with photon therapy?
Does dual immune checkpoint inhibition with atezolizumab and tiragolumab improve outcomes after chemoradiation for unresectable esophageal squamous cell carcinoma.
A recent study found that mean dose to what mediastinal organ was associated with increased risk of distant metastasis?
Answers
Yes. Among patients receiving adjuvant RT to the unilateral primary site and neck, acute grade 2+ mucositis was lower with protons, though there were no differences in late effects, patient reported outcomes, or treatment outcomes.
No. In SKYSCRAPER-07, this combination did not improve PFS or OS. Interestingly, both PFS and OS were better than placebo with atezolizumab alone.
Thymus. This study found that keeping mean thymus dose <35 Gy was associated with less detriment in radiographic measures of thymic function. | QuadShot News
Does dual immune checkpoint inhibition with atezolizumab and tiragolumab improve outcomes after chemoradiation for unresectable esophageal squamous cell carcinoma.
A recent study found that mean dose to what mediastinal organ was associated with increased risk of distant metastasis?
Answers
Yes. Among patients receiving adjuvant RT to the unilateral primary site and neck, acute grade 2+ mucositis was lower with protons, though there were no differences in late effects, patient reported outcomes, or treatment outcomes.
No. In SKYSCRAPER-07, this combination did not improve PFS or OS. Interestingly, both PFS and OS were better than placebo with atezolizumab alone.
Thymus. This study found that keeping mean thymus dose <35 Gy was associated with less detriment in radiographic measures of thymic function. | QuadShot News

